Recent dynamics in Neisseria gonorrhoeae genomic epidemiology in Brazil: antimicrobial resistance and genomic lineages in 2017-20 compared to 2015-16

A study conducted in 11 Brazilian cities between 2017 and 2020 revealed a significant increase in gonorrhoea resistance, mainly due to clonal expansions of strains with 23S rRNA C2611T and mtr mosaics. The study also found that resistance to ceftriaxone and cefixime remained at the same levels as in 2015-16. The study concluded that enhanced gonococcal AMR surveillance, including WGS, is crucial in Brazil and other Latin American and Caribbean countries to understand the shifting gonorrhoea epidemiology.